Synthesized peptide derived from human SUMO2 AA range: 45-95
Alternative Synonym:
Small ubiquitin-related modifier 2 (SUMO-2,HSMT3,SMT3 homolog 2,SUMO-3,Sentrin-2,Ubiquitin-like protein SMT3A,Smt3A)
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
