The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/beta/delta around the phosphorylation site of Thr305. AA range:271-320
Alternative Synonym:
CAMK2A, CAMKA, KIAA0968, Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2B, CAM2, CAMK2, CAMKB, Calcium/calmodulin-dependent protein kinase type II subunit beta, Ca
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Western Blot analysis of various cells using Phospho-CaMKIIalpha/beta/delta (T305) Polyclonal Antibody diluted at 1:1000
Western Blot analysis of 453 cells using Phospho-CaMKIIalpha/beta/delta (T305) Polyclonal Antibody diluted at 1:1000
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using CaMK2 alpha/beta/delta (Phospho-Thr305) Antibody
Immunohistochemistry analysis of paraffin-embedded human brain, using CaMK2 alpha/beta/delta (Phospho-Thr305) Antibody. The picture on the right is blocked with the phospho peptide.
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