MEF-2 (phospho Ser408) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: MEF-2 (phospho Ser408) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES1509
• Hersteller Artikelnummer: ES1509
• Alternativnummer: EBT-ES1509-50, EBT-ES1509-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human MEF2A around the phosphorylation site of Ser408. AA range:374-423
• Alternative Synonym: MEF2A, MEF2, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1

Produktbeschreibung

The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 55kD
• NCBI: 4205
• UniProt: Q02078

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Bilder

Western Blot analysis of various cells using Phospho-MEF-2 (S408) Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using MEF2A (Phospho-Ser408) Antibody

Immunofluorescence analysis of HeLa cells treated with PMA 125ng/ml 30, using MEF2A (Phospho-Ser408) Antibody. The picture on the right is blocked with the phospho peptide.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using MEF2A (Phospho-Ser408) Antibody. The picture on the right is blocked with the phospho peptide.