DARPP-32 (phospho Thr34) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: DARPP-32 (phospho Thr34) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES1523
• Hersteller Artikelnummer: ES1523
• Alternativnummer: EBT-ES1523-50, EBT-ES1523-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human DARPP-32 around the phosphorylation site of Thr34. AA range:18-67
• Alternative Synonym: PPP1R1B, DARPP32, Protein phosphatase 1 regulatory subunit 1B, DARPP-32, Dopamine- and cAMP-regulated neuronal phosphoprotein

Produktbeschreibung

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 35kD
• NCBI: 84152
• UniProt: Q9UD71

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Bilder

Western Blot analysis of various cells using Phospho-DARPP-32 (T34) Polyclonal Antibody diluted at 1:1000

Western Blot analysis of RAT-musle cells using Phospho-DARPP-32 (T34) Polyclonal Antibody diluted at 1:1000

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using DARPP-32 (Phospho-Thr34) Antibody

Immunofluorescence analysis of HepG2 cells, using DARPP-32 (Phospho-Thr34) Antibody. The picture on the right is blocked with the phospho peptide.