The antiserum was produced against synthesized peptide derived from human ABCB7. AA range:691-740
Alternative Synonym:
ABCB7, ABC7, ATP-binding cassette sub-family B member 7, mitochondrial, ATP-binding cassette transporter 7, ABC transporter 7 protein
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms hav
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Western Blot analysis of various cells using ABCB7 Polyclonal Antibody diluted at 1:1000
Western Blot analysis of various cells using antibody diluted at 1:1000. Secondary antibody(catalog:RS0002) was diluted at 1:20000
Immunohistochemistry analysis of paraffin-embedded human thymus gland, using ABCB7 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HUVECcells using ABCB7 antibody.
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