Akt2 rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Akt2 rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES1636
• Hersteller Artikelnummer: ES1636
• Alternativnummer: EBT-ES1636-50, EBT-ES1636-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human Akt2. AA range:432-481
• Alternative Synonym: AKT2, RAC-beta serine/threonine-protein kinase, Protein kinase Akt-2, Protein kinase B beta, PKB beta, RAC-PK-beta

Produktbeschreibung

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 56kD
• NCBI: 208
• UniProt: P31751

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Bilder

Western Blot analysis of various cells using Akt2 Polyclonal Antibody diluted at 1:500

Western Blot analysis of 3T3 cells using Akt2 Polyclonal Antibody diluted at 1:500

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Akt2 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from A2780 cells, treated with TNF-alpha, using Akt2 Antibody. The lane on the right is blocked with the synthesized peptide.