The antiserum was produced against synthesized peptide derived from human ATRIP. AA range:34-83
Alternative Synonym:
ATRIP, AGS1, ATR-interacting protein, ATM and Rad3-related-interacting protein
This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012],
