The antiserum was produced against synthesized peptide derived from human Ik3-1. AA range:561-610
Alternative Synonym:
CABLES1, CABLES, CDK5 and ABL1 enzyme substrate 1, Interactor with CDK3 1, Ik3-1
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
