Caspase-2 rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Caspase-2 rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES1853
• Hersteller Artikelnummer: ES1853
• Alternativnummer: EBT-ES1853-50, EBT-ES1853-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human Caspase 2. AA range:123-172
• Alternative Synonym: CASP2, ICH1, NEDD2, Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1

Produktbeschreibung

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimers disease, Huntingtons disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 51kD
• NCBI: 835
• UniProt: P42575

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Bilder

Western Blot analysis of various cells using Caspase-2 Polyclonal Antibody

Western Blot analysis of K562 cells using Caspase-2 Polyclonal Antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 2 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from K562, using Caspase 2 Antibody. The lane on the right is blocked with the synthesized peptide.