ITGA5 (heavy chain, Cleaved-Arg894) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: ITGA5 (heavy chain, Cleaved-Arg894) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES20006
• Hersteller Artikelnummer: ES20006
• Alternativnummer: EBT-ES20006-50, EBT-ES20006-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC, WB
• Spezies Reaktivität: Human, Mouse
• Immunogen: Synthesized peptide derived from human ITGA5 (heavy chain, Cleaved-Arg894)
• Alternative Synonym: Integrin alpha-5 (CD49 antigen-like family member E,Fibronectin receptor subunit alpha,Integrin alpha-F,VLA-5,CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain, Integrin alpha-5 light chain]

Produktbeschreibung

function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 94 110kD
• NCBI: 3678
• UniProt: P08648

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000

Bilder

Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).