ITGAE (light chain, Cleaved-Arg177) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: ITGAE (light chain, Cleaved-Arg177) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES20010
• Hersteller Artikelnummer: ES20010
• Alternativnummer: EBT-ES20010-50, EBT-ES20010-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from human ITGAE (light chain, Cleaved-Arg177)
• Alternative Synonym: Integrin alpha-E (HML-1 antigen,Integrin alpha-IEL,Mucosal lymphocyte 1 antigen,CD antigen CD103) [Cleaved into: Integrin alpha-E light chain, Integrin alpha-E heavy chain]

Produktbeschreibung

integrin subunit alpha E(ITGAE) Homo sapiens Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 17 128kD
• NCBI: 3682
• UniProt: P38570

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-2000,IHC-p 1:50-300

Bilder

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).