PROC (light chain, Cleaved-Leu179) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: PROC (light chain, Cleaved-Leu179) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES20045
• Hersteller Artikelnummer: ES20045
• Alternativnummer: EBT-ES20045-50, EBT-ES20045-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179)
• Alternative Synonym: Vitamin K-dependent protein C (EC 3.4.21.69,Anticoagulant protein C,Autoprothrombin IIA,Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain, Vitamin K-dependent protein C heavy chain, Activation peptide]

Produktbeschreibung

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 17 45kD
• NCBI: 5624
• UniProt: P04070

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000

Bilder

Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).