PDK1 (Phospho Tyr243) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: PDK1 (Phospho Tyr243) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES20214
• Hersteller Artikelnummer: ES20214
• Alternativnummer: EBT-ES20214-50, EBT-ES20214-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from human PDHK1 (Phospho Tyr243)
• Alternative Synonym: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (EC 2.7.11.2,Pyruvate dehydrogenase kinase isoform 1)

Produktbeschreibung

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 50kD
• NCBI: 5163
• UniProt: Q15118

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000

Bilder

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).