STIP1/HOP Rabbit pAb, Polyclonal

Produktübersicht

• Artikelname: STIP1/HOP Rabbit pAb, Polyclonal
• Artikelnummer: EBT-ES20870
• Hersteller Artikelnummer: ES20870
• Alternativnummer: EBT-ES20870-50, EBT-ES20870-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from human STIP1/HOP AA range: 250-300
• Alternative Synonym: Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)

Produktbeschreibung

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A, MIM 140550) and HSP90 (see HSP90AA1, MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 64kD
• NCBI: 10963
• UniProt: P31948

Anwendungsbeschreibung

• Application Verdünnung: IHC-p1:50-200 ,WB 1:1000-2000

Bilder

Western blot analysis of 1)Hela Cell, 2) 293T Cell, 3)Mouse Brain Tissue, 4) Rat Brain Tissue Lysate using STIP1/HOPRabbit polyclonal Antibody diluted at 1:2,000.

Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).