Synthesized peptide derived from DNA Ligase III . at AA range: 110-190
Alternative Synonym:
LIG3, DNA ligase 3, DNA ligase III, Polydeoxyribonucleotide synthase [ATP] 3
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Western Blot analysis of various cells using DNA Ligase III Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western Blot analysis of MCF7 cells using DNA Ligase III Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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