This gene encodes an endo/exonuclease with 5-3 exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5 end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009],
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Western Blot analysis of various cells using Endo G-L1 Polyclonal Antibody
Western blot analysis of lysates from HUVEC, HT-29, and HepG2 cells, using ENDOGL1 Antibody. The lane on the right is blocked with the synthesized peptide.
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