GCSc-gamma rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: GCSc-gamma rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES2414
• Hersteller Artikelnummer: ES2414
• Alternativnummer: EBT-ES2414-50, EBT-ES2414-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human GCSc-gamma. AA range:266-315
• Alternative Synonym: GCLC, GLCL, GLCLC, Glutamate--cysteine ligase catalytic subunit, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase

Produktbeschreibung

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 73kD
• NCBI: 2729
• UniProt: P48506

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Bilder

Western Blot analysis of various cells using GCSc-gamma Polyclonal Antibody

Western blot analysis of lysate from A549 cells, using GCSc-gamma antibody.