The antiserum was produced against synthesized peptide derived from human TBX3. AA range:271-320
Alternative Synonym:
TBX3, T-box transcription factor TBX3, T-box protein 3, TBX2, T-box transcription factor TBX2, T-box protein 2
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008],
