The antiserum was produced against synthesized peptide derived from the Internal region of human CUL4B. AA range:711-760
Alternative Synonym:
CUL4B, KIAA0695, Cullin-4B, CUL-4B
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
