CENP-A rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: CENP-A rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES4512
• Hersteller Artikelnummer: ES4512
• Alternativnummer: EBT-ES4512-50, EBT-ES4512-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human Centromeric Protein A. AA range:1-50
• Alternative Synonym: CENPA, Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-A

Produktbeschreibung

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• NCBI: 1058
• UniProt: P49450

Anwendungsbeschreibung

• Application Verdünnung: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Bilder

Immunofluorescence analysis of HepG2 cells, using Centromeric Protein A Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Centromeric Protein A Antibody. The picture on the right is blocked with the synthesized peptide.