COL9A1 rabbit pAb, Rabbit, Polyclonal

Artikelnummer: EBT-ES4750
Artikelname: COL9A1 rabbit pAb, Rabbit, Polyclonal
Artikelnummer: EBT-ES4750
Hersteller Artikelnummer: ES4750
Alternativnummer: EBT-ES4750-50, EBT-ES4750-100
Hersteller: ELK Biotechnology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IF, IHC, WB
Spezies Reaktivität: Human, Mouse
Immunogen: Synthesized peptide derived from COL9A1 . at AA range: 390-470
Alternative Synonym: COL9A1, Collagen alpha-1(IX) chain
This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Klonalität: Polyclonal
Konzentration: 1 mg/ml
Molekulargewicht: 120kD
NCBI: 1297
UniProt: P20849
Application Verdünnung: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Western Blot analysis of HepG2 cells using COL9A1 Polyclonal Antibody
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).