The antiserum was produced against synthesized peptide derived from human MAK around the phosphorylation site of Tyr159. AA range:126-175
Alternative Synonym:
MAK, Serine/threonine-protein kinase MAK, Male germ cell-associated kinase
The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Western blot analysis of lysates from HepG2 cells treated with PMA 125ng/ml 30, using MAK (Phospho-Tyr159) Antibody. The lane on the right is blocked with the phospho peptide.
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