Tau (phospho Ser519) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Tau (phospho Ser519) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES6178
• Hersteller Artikelnummer: ES6178
• Alternativnummer: EBT-ES6178-50, EBT-ES6178-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human Tau around the phosphorylation site of Ser519/202. AA range:266-315
• Alternative Synonym: MAPT, MAPTL, MTBT1, TAU, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau

Produktbeschreibung

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimers disease, Picks disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 50-85kD
• NCBI: 4137
• UniProt: P10636

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Bilder

Western blot analysis of lysates from Jurkat cells treated with H2O2 100uM 30, using Tau (Phospho-Ser519/202) Antibody. The lane on the right is blocked with the phospho peptide.