FMIP rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: FMIP rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES7821
• Hersteller Artikelnummer: ES7821
• Alternativnummer: EBT-ES7821-50, EBT-ES7821-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human THOC5. AA range:561-610
• Alternative Synonym: THOC5, C22orf19, KIAA0983, THO complex subunit 5 homolog, Functional spliceosome-associated protein 79, fSAP79, NF2/meningioma region protein pK1.3, Placental protein 39.2, PP39.2, hTREX90

Produktbeschreibung

function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R, which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 78kD
• NCBI: 8563
• UniProt: Q13769

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Bilder

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using THOC5 Antibody. The picture on the right is blocked with the synthesized peptide.