The antiserum was produced against synthesized peptide derived from human Caveolin 2 around the phosphorylation site of Tyr27. AA range:12-61
Alternative Synonym:
CAV2, Caveolin-2
The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011],
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Western blot analysis of lysates from HepG2 cells treated with EGF 200ng/ml 5 , using Caveolin 2 (Phospho-Tyr27) Antibody. The lane on the right is blocked with the phospho peptide.
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