MYBPC3 rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: MYBPC3 rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES8931
• Hersteller Artikelnummer: ES8931
• Alternativnummer: EBT-ES8931-50, EBT-ES8931-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from human MYBPC3 Polyclonal
• Alternative Synonym: Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)

Produktbeschreibung

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 140kD
• NCBI: 4607
• UniProt: Q14896

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-2000,IHC-p 1:50-300

Bilder

Western blot analysis of mouse-kidney lysate, antibody was diluted at 1000. Secondary antibody(catalog:RS0002) was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).