ET Receptor Antagonist (PD 145065), CAS [[153049-49-1]]

Produktübersicht

• Artikelname: ET Receptor Antagonist (PD 145065), CAS [[153049-49-1]]
• Artikelnummer: ECH-331-18-5MG
• Hersteller Artikelnummer: 331-18-5mg
• Alternativnummer: ECH-331-18-5MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

CAS Number: 153049-49-1Molecular Weight: 950.15Salt Form: Na+Purity: >96%Sequence (3-letter): Ac-D-Bhg-Leu-Asp-Ile-Ile-Trp-OHSequence (1-letter): Ac-(D-Bhg)LDIIW-OHStorage: -20 AC or belowSolubility: water PBS and DMSO 1 mg/mlD-Bhg = D-5H-Dibenzo[a d]cycloheptene-5-acetic acidET Antagonist PD 145065 is used as an endothelin-A/endothelin-B (ETA/ETB) receptor antagonist. PD 145065 is also a growth factor that binds to G protein-coupled receptors and serves as a useful model to study mitogenic signal transduction by vasoactive peptides.References1. Kanagy N.L. et al. (2001) a€Role of Endothelin in Intermittent Hypoxia-Induced Hypertensiona€ 37 (2 Pt 2): 511-5.2. Bourque S.L. et al (2012) a€Role of endothelin-1 in the hyper-responsiveness to nitrovasodilators following acute NOS inhibitiona€ Br. J. Pharmacol. 165 (6): 1992-1999.3. Dobrowolski L. (2003) a€Cardiovascular and renal effects of endothelin receptor blockade with PD 145065 and interaction with urodilatina€ Acta Physiol. Scand. 159 (1): 7-13.

Produkteigenschaften

• Tag: 210 1180 1226 1178 1225 312 207
• CAS Nummer: [153049-49-1]