Urocortin is closely related to corticotropin-releasing factor (CRF) and is widely expressed throughout the nervous system of mammals. Urocortin interacts with the CRF1 and CRF2 receptors and is important in stress-responses and appetite. Urotropin will cause an increase in heart rate and coronary blood flow through binding to CRF2 receptor and can prevent cardiac tissue damage from ischemic injury.CAS Number: 176591-49-4Molecular Weight: 4693.52Salt Form: TFAPurity: >95%Sequence (3-letter): Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2Sequence (1-letter): DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV-NH2Storage: -20 AC or belowReferencesKishimoto T Pearse RV 2nd Lin CR Rosenfeld MG. A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle [published correction appears in Proc Natl Acad Sci U S A 1995 Apr 25,92(9):4074]. Proc Natl Acad Sci U S A. 1995,92(4):1108-1112. doi:10.1073/pnas.92.4.1108
Tag:
1192
CAS Nummer:
[176591-49-4]
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