CAS Number: 17650-98-5Molecular Weight: 1352.43Salt Form: N/APurity: >95%Sequence (3-letter): Glp-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2 (Glp = Pyroglutamic acid)Sequence (1-letter): (Glp)QD(Tyr(SO3H))TGWMDF-NH2Storage: -20 AC or belowSolubility: water >1 mg/mLCaerulein is a sulfated peptide that is used in the study of NF-iB-mediated signaling. When administered via i.v. it can produce analgesia. It has also been shown to induce pancreatitis in animals at high doses and prevent pain associated with gall-bladder contraction and intermittent claudication.References1. Baber N.S. Dourish C.T. and Hill D.R. (1989) a€The role of CCK caerulein and CCK antagonists in nociceptiona€ Pain 9: 307-328.2.Watanabe O. et al (1984) a€Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitisa€ Am. J. Physiol. 246(4 Pt 1): G457-67.
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[17650-98-5]
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