CAS Number: 133407-83-7 Molecular Weight: 475.3 Salt Form: N/A Purity: >95% Sequence (3-letter): Z-Leu-Leu-Nle-CHO Sequence (1-letter): Z-LL(Nle)-CHO Storage: -20 ?C or below Solubility: DMSO > 1 mg/mL Gamma Secretase Inhibitor, sequence Z-Leu-Leu-Nle-CHO (Z-Leu-Leu-Nle-al), is a leupeptin analog which inhibits gamma secretase. Gamma secretase is a membrane associated protein complex consisting of presenilin, nicastrin, Aph-1, and Pen-2. It catalyzes the cleavage of Notch and Beta Amyloid proteins and is implicated in Alzheimers disease.
Anwendungsbeschreibung:
Categories: Peptides. Related: Central Nervous System, Inhibitor. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature
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