Molecular Weight: 541.65Salt Form: TFAPurity: >96%Sequence (3-letter): D-Ile-Pro-Arg-AMCSequence (1-letter): iPR-AMCStorage: -20 AC or belowD-Ile-Pro-Arg-AMC is a fluorogenic substrate for tissue plasminogen-activator (tPA) a serine protease found on endothelial cells lining blood vessels. tPA is the major enzyme responsible for clot breakdown by converting plasminogen to plasmin.Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.
Tag:
1179
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