Ac-Val-Glu-Ile-Asp-pNA (Caspase 6 (Mch2) Substrate), CAS [[189684-54-6]]
Artikelnummer:
ECH-860-50-25MG
Hersteller Artikelnummer:
860-50-25mg
Alternativnummer:
ECH-860-50-25MG
Hersteller:
Echelon Biosciences
Kategorie:
Molekularbiologie
CAS Number: 189684-54-6 Molecular Weight: 636.28 Salt Form: N/A Purity: >96% Sequence (3-letter): Ac-Val-Glu-Ile-Asp-pNA Sequence (1-letter): Ac-VEID-pNA Storage: -20 AC or belowAc-Val-Glu-Ile-Asp-pNA is a colorimetric substrate for Caspase 6. Caspase 6 (Mch2) is a cysteine protease involved in the execution phase of apoptosis mediating neuronal shrinkage. In addition it has important roles in neurodegenerative disorders such as Huntingtona€(TM)s Parkinsona€(TM)s and Alzheimera€(TM)s diseases. Caspase 6 cleaves the mutated huntintin protein and the amyloid precursor protein resulting in the aggregating protein fragments typical of Huntingtona€(TM)s and Alzheimera€(TM)s diseases respectively.Activity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm.
Tag:
1208 1179
CAS Nummer:
[189684-54-6]
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