Caspase 6 (Mch2) Substrate, fluorogenic

Produktübersicht

• Artikelname: Caspase 6 (Mch2) Substrate, fluorogenic
• Artikelnummer: ECH-860-52
• Hersteller Artikelnummer: 860-52
• Alternativnummer: ECH-860-52-25MG,ECH-860-52-5MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

CAS Number: 219137-97-0 Molecular Weight: 673.3 Salt Form: N/A Purity: >96% Sequence (3-letter): Ac-Val-Glu-Ile-Asp-AMC Sequence (1-letter): Ac-VEID-AMC Storage: -20 ?C or below Solubility: DMSO, phosphate buffer pH 7.5 Ac-VEID-AMC is a fluorogenic substrate for caspase 6 (Mch-2?), a member of the cysteine-aspartate protease family, which play a central role in the execution-phase of apoptosis. The excitation/emission maximum of AMC is 340-360/440-460 nm, respectively. Ac-VEID-AMC is based on lamin A site of cleavage.

References

1. Benford, H.L. et al. (2001) ?Visualization of bisphosphonate-induced caspase-3 activity in apoptotic osteoclasts in vitro? 28 (5): 465?473. 2. Rouaux, C. e al. (2003) ?Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration? EMBO J. 22 (24): 6537?6549.

Anwendungsbeschreibung

• Anwendungsbeschreibung: Categories: Peptides. Related: Caspase, Enzyme Substrates. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature