Molecular Weight: 690.36Salt Form: HClPurity: >96%Sequence (3-letter): Z-Ala-Arg-Arg-4MbNASequence (1-letter): Z-ARR-4MbNAStorage: -20 AC or belowZ-Ala-Arg-Arg-4MbNA is a fluorogenic substrate for Cathepsin B. Cathepsin B is a lysosomal cysteine protease with a role in intracellular protein degradation. Cathepsin B crosses the blood-brain barrier and elevated levels are implicated in many neurological maladies including traumatic brain injury epilepsy and Alzheimers disease.Activity is quantified by release of free fluorescent 4-Methoxy-i-naphthylamine (4MiNA) which excites at 335-350 nm and emits at 410-440 nm
Tag:
1179
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