Dnp-Pro-Leu-Ala-Tyr-Trp-Ala-Arg-OH (MMP-8 Substrate)

Produktübersicht

• Artikelname: Dnp-Pro-Leu-Ala-Tyr-Trp-Ala-Arg-OH (MMP-8 Substrate)
• Artikelnummer: ECH-868-44-25MG
• Hersteller Artikelnummer: 868-44-25mg
• Alternativnummer: ECH-868-44-25MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

Molecular Weight: 1041.47Salt Form: TFAPurity: >96%Sequence (3-letter): Dnp-Pro-Leu-Ala-Tyr-Trp-Ala-Arg-OHSequence (1-letter): Dnp-PLAYWAR-OHStorage: -20 AC or belowDnp-Pro-Leu-Ala-Tyr-Trp-Ala-Arg-OH is a fluorogenic substrate for matrix metalloprotease 8 (MMP-8) and MMP-26. MMP-8 (neutrophil collagenase) primarily degrades type I II & III collagen in the extracellular matrix. Reduced MMP-8 activity in a murine breast cancer model leads to increased tumor growth and vascularity in addition to immune cell infiltration.Activity is quantified by tryptophan fluorescence (Ex 280 nm Em at 360 nm).

Produkteigenschaften

• Tag: 1179