Suc-Ala-Leu-Pro-Phe-AMC (PPIase Substrate), CAS [[142997-31-7]]

Produktübersicht

• Artikelname: Suc-Ala-Leu-Pro-Phe-AMC (PPIase Substrate), CAS [[142997-31-7]]
• Artikelnummer: ECH-869-20-10MG
• Hersteller Artikelnummer: 869-20-10mg
• Alternativnummer: ECH-869-20-10MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

CAS Number: 142997-31-7Molecular Weight: 702.31Salt Form: N/APurity: >96%Sequence (3-letter): Suc-Ala-Leu-Pro-Phe-AMCSequence (1-letter): Suc-ALPF-AMCStorage: -20 AC or belowSuc-ALPF-AMC is a fluorogenic substrate for peptidyl prolyl cis-trans isomerases (PPIases) including FK-506 binding proteins (FKBPs also called macrophilins) and cyclophilins. PPIases or rotamases catalyze the cis-trans isomerisation of proline imidic peptide bonds to accelerate protein folding.Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.References:1) Ishikawa Y BAchinger HP. A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis. J Biol Chem. 2014 Jun 27,289(26):18189-201. doi: 10.1074/jbc.M114.561944.

Produkteigenschaften

• Tag: 1179
• CAS Nummer: [142997-31-7]