Bz-Arg-Gly-Phe-Phe-Pro-4MbNA (Cathepsin D Substrate)

Produktübersicht

• Artikelname: Bz-Arg-Gly-Phe-Phe-Pro-4MbNA (Cathepsin D Substrate)
• Artikelnummer: ECH-880-42-1MG
• Hersteller Artikelnummer: 880-42-1mg
• Alternativnummer: ECH-880-42-1MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

Molecular Weight: 881.42Salt Form: HClPurity: >96%Sequence (3-letter): Bz-Arg-Gly-Phe-Phe-Pro-4MbNASequence (1-letter): Bz-RGFFP-4MbNAStorage: -20 AC or belowBz-Arg-Gly-Phe-Phe-Pro-4MbNA is a fluorogenic substrate for Cathepsin D. Cathepsin D is a lysosomal aspartyl protease whose role is to degrade and activate intracellular proteins including hormones enzyme precursors and growth factors. Over expression in tumors stimulates metastasis and considered a marker of poor prognosis in breast cancer.Activity is quantified by release of free fluorescent 4-Methoxy-i-naphthylamine (4MiNA) which excites at 335-350 nm and emits at 410-440 nm.

Produkteigenschaften

• Tag: 1208 1179