CAS Number: 70967-90-7 Molecular Weight: 590.27 Salt Form: N/A Purity: >96% Sequence (3-letter): MeOSuc-Ala-Ala-Pro-Val-pNA Sequence (1-letter): MeOSuc-AAPV-pNA Storage: -20 ?C or below Solubility: DMSO (20 mM), methanol (1 mg/ml), DMF, and ethanol Pancreatic Leukocyte Elastase Substrate (MeOSuc-AAPV-pNA), aka Elastase Substrate 1, is a highly sensitive colorimetric substrate for pancreatic leukocyte elastase (neutrophil elastase). Pancreatic leukocyte elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy bacteria as well as host tissue. MeOSuc-AAPV-pNA can be used for in vitro assays with purified enzyme or with biological fluids or conditioned medium. Reaction progress is detected by monitoring substrate hydrolysis at 405-410 nm. This product is not a substrate for cathepsin G or chymotrypsin.
