Pancreatic Leukocyte Elastase Substrate colorimetric, CAS [[70967-90-7]]

Produktübersicht

• Artikelname: Pancreatic Leukocyte Elastase Substrate colorimetric, CAS [[70967-90-7]]
• Artikelnummer: ECH-881-15-5MG
• Hersteller Artikelnummer: 881-15-5mg
• Alternativnummer: ECH-881-15-5MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

CAS Number: 70967-90-7Molecular Weight: 590.27Salt Form: N/APurity: >96%Sequence (3-letter): MeOSuc-Ala-Ala-Pro-Val-pNASequence (1-letter): MeOSuc-AAPV-pNAStorage: -20 AC or belowSolubility: DMSO (20 mM) methanol (1 mg/ml) DMF and ethanolPancreatic Leukocyte Elastase Substrate (MeOSuc-AAPV-pNA) aka Elastase Substrate 1 is a highly sensitive colorimetric substrate for pancreatic leukocyte elastase (neutrophil elastase). Pancreatic leukocyte elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy bacteria as well as host tissue. MeOSuc-AAPV-pNA can be used for in vitro assays with purified enzyme or with biological fluids or conditioned medium. Reaction progress is detected by monitoring substrate hydrolysis at 405-410 nm.This product is not a substrate for cathepsin G or chymotrypsin.References1. A.M. et al. (2002) a€Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritisa€ J. Clin. Invest. 109 (3): 363a€''371.2. Lonky S. A and Whole H. (1983) a€Regulation of elastolysis of insoluble elastin by human leukocyte elastase: stimulation by lysine rich lugans anionic detergents and ionic strengtha€ Biochemistry 22: 3714.3. Stein R. L. Viscarello B. R. and Vildonger R. A. (1984) a€Catalysis by human leukocyte elastase. II. Rate limiting deacylation for specific p-nitroanilides and amidesa€ J. Am. Chem. Soc.. 106: 796.

Produkteigenschaften

• Tag: 1303 1179 1304 1305
• CAS Nummer: [70967-90-7]