AS1938909 (SHIP2 Inhibitor)

Produktübersicht

• Artikelname: AS1938909 (SHIP2 Inhibitor)
• Artikelnummer: ECH-B-0343
• Hersteller Artikelnummer: B-0343
• Alternativnummer: ECH-B-0343-10MG,ECH-B-0343-25MG,ECH-B-0343-5MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

AS1938909 is a potent SHIP2 inhibitor (Ki = 0.44uM). This compound shows signficant selectivity over some related phosphatases (IC50 = 0.18uM, 21uM, >50uM for mSHIP2, hSHIP2, hPTEN respectively). It also enhances Akt phosphorylation and increases glucose consumption and uptake in L6 myotubes.

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Storage

2-8 C

References

A Suwa, T Yamanoto et al. Glucose metabolism activation by SHIP2 inhibitors via up-regulation of GLUT1 gene in L6 myotubes Eur J Pharmaco, 2010, 642, 177

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Documents

Technical Data Sheet

Anwendungsbeschreibung

• Anwendungsbeschreibung: Categories: Biochemical Reagents. Related: Inhibitor, SHIP. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature