Biotin Phosphatidylinositol 3,5-bisphosphate

Artikelnummer: ECH-C-35B6
Artikelname: Biotin Phosphatidylinositol 3,5-bisphosphate
Artikelnummer: ECH-C-35B6
Hersteller Artikelnummer: C-35B6
Alternativnummer: ECH-C-35B6-10UG,ECH-C-35B6-50UG
Hersteller: Echelon Biosciences
Kategorie: Molekularbiologie
Biotin Phosphatidylinositol 3,5-bisphosphate is a water soluble analog of PI(3,5)P2 labeled with biotin at the sn-1 position.
Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,5-bisphosphate is in very low abundance and is required for retrograde membrane trafficking from lysosomal and late endosomal compartments to the Golgi and is involved in autophagy. PI(3,5)P2 levels are controlled by the 5-kinase PIKfyve and the 5-phosphatase Fig4/Sac3 and disregulation is linked to several human neuropathies (eg Chacot-Marie-Tooth disease). Bulk discounts available, please email echelon echelon-inc.com for information.

Documents

Technical Data Sheet
Anwendungsbeschreibung: Categories: Lipids. Related: Biotinylated, PI(3\,5)P2. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination