HA30-TexasRed

Artikelnummer: ECH-H-025R
Artikelname: HA30-TexasRed
Artikelnummer: ECH-H-025R
Hersteller Artikelnummer: H-025R
Alternativnummer: ECH-H-025R-10MG
Hersteller: Echelon Biosciences
Kategorie: Molekularbiologie
HA30-TexasRed is made up of hyaluronic acid labeled with the red fluorophore Texas Red Average MW: 24 kDa
Hyaluronic acid (HA) is a high molecular weight anionic polysaccharide (1,000-10,000 kD) composed of repeating disaccharides and is one of several glycosaminoglycan components of the extracellular matrix of connective tissue. Free HA is taken up by the liver where it is degraded and recycled. Many chronic liver diseases, including infection (hepatitis B or C), toxicity (alcohol and drugs), genetic (hemochromatosis), autoimmunity, and malignancy, result in liver inflammation which can progress to liver fibrosis and cirrhosis, causing impairment of liver function and resulting in a rapid increase in circulating HA levels. Data indicates a relationship between HA levels, local inflammation and severity of disease. Recent publications have also shown that HA levels in urine are indicative of bladder cancer, that HA levels are directly correlated to liver disease, and suggests enhanced breakdown of HA in the lungs of patients with chronic obstructive pulmonary disease. In addition, serum levels of HA have been found to be elevated in patients with rheumatoid arthritis. Absorption/Emission: 589/615nm

Storage

-20C, protected from light

Documents

Technical Data Sheet
Anwendungsbeschreibung: Categories: Biochemical Reagents. Related: Fluorescent, Hyaluronic Acid. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature