LPA Beads
Artikelnummer:
ECH-L-6101
Produktübersicht
Artikelname:
LPA Beads
Artikelnummer:
ECH-L-6101
Hersteller Artikelnummer:
L-6101
Alternativnummer:
ECH-L-6101-100UL, ECH-L-6101-1ML
Hersteller:
Echelon Biosciences
Kategorie:
Molekularbiologie
Produktbeschreibung
LPA beads are composed of agarose with 10 nanomoles of bound Lyosphosphatidic Acid (LPA) per mL of beads, enough for several protein binding experiments. Each 1 mL order of LPA Beads includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase. Storage 4 C - do not freeze Applications LPA Beads are designed for use in protein pull-down experiments to identify and characterize LPA binding proteins. Possible applications include the isolation of lipid-binding proteins present in a cell lysate or in a mixture of in vitro translated peptides, for separation by SDS-PAGE and further analysis. Featured in Publications 1) 1. A. S. Nieto-Posadas, G. Picazo-JuArez, et al. (2012) Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site Nat Chem Biol 8(1), 78-85 doi:10.1038/nchembio.712 2) R. Tsukahara, H. Haniu, et al. (2014) Heart-type fatty-acid-binding protein (FABP3) is a lysophosphatidic acid-binding protein in human coronary artery endothelial cells FEBS Open Bio 4(1), 947-951 DOI: 10.1016/j.fob.2014.10.014 3) S. L. Morales-Lazaro, B. Serrano-Flores, et al. (2014) Structural Determinants of the Transient Receptor Potential 1 (TRPV1) Channel Activation by Phospholipid Analogs J. Biol. Chem. 289(35), 24079-24090 10.1074/jbc.M114.572503 Being bio-reactive blog: Lipid-Ligand interaction tools: lipids are not scary intermediates anymore Documents Technical Data Sheet
Anwendungsbeschreibung
Anwendungsbeschreibung:
Categories: Biochemical Reagents. Related: Beads, Lysophosphatidic Acid. Ship 1 : Shipping Temp. Ship 2: Gel Ice