Thio-ccPA, CAS [[779333-56-1]]

Produktübersicht

• Artikelname: Thio-ccPA, CAS [[779333-56-1]]
• Artikelnummer: ECH-L-7118-500UG
• Hersteller Artikelnummer: L-7118-500ug
• Alternativnummer: ECH-L-7118-500UG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

Thio-ccPA is a stabilized analogue of carbacyclic phosphatidic acid (ccPA). It inhibits the lysoPLD activity of Autotaxin (ATX) and acts as an LPA1/3 receptor antagonist. Thio-ccPA decreases the viability of B16F10 A375 and MeWo melanoma cell lines. Addition of endogenous LPA did not reverse these effects in B16F10 cells. Thio-ccPA decreased the number of pulmonary and non-pulmonary metastases in a B16F10 metastatic melanoma mouse model.

Produkteigenschaften

• Tag: 742 743 443 744
• CAS Nummer: [779333-56-1]