N2-3L

Produktübersicht

• Artikelname: N2-3L
• Artikelnummer: ECH-N-1034
• Hersteller Artikelnummer: N-1034
• Alternativnummer: ECH-N-1034-10MG, ECH-N-1034-1MG, ECH-N-1034-25MG, ECH-N-1034-5MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

A novel supramolecular lipid nanoparticle (SMLNP) delivery platform has been developed, consisting of an ionizable lipid (N2-3L) for delivering tumor antigen mRNA, and a beta-cyclodextrin (beta-CD)-modified ionizable lipid (Lip-CD) for encapsulating the Toll-like receptor 7/8 (TLR7/8) agonist R848. The combination of the mRNA vaccine and R848 significantly enhanced dendritic cell maturation and antigen presentation, resulting in superior antitumor efficacy in vivo.

Anwendungsbeschreibung

• Anwendungsbeschreibung: Categories: Ionizable Lipids, Lipids