Lipid M

Produktübersicht

• Artikelname: Lipid M
• Artikelnummer: ECH-N-1103
• Hersteller Artikelnummer: N-1103
• Alternativnummer: ECH-N-1103-10MG, ECH-N-1103-25MG, ECH-N-1103-5MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

Lipid M is an ionizable lipid used to form lipid nanoparticles for delivering RNA. LNPs formulated with Lipid M delivered luciferase mRNA in mice resulting in higher protein expression compared to the benchmark lipid DLin-MC3-DMA. Lipid M LNPs delivering IgG mRNA showed prolonged expression compared to MC3 in non-human primates after intramuscular injection. LNPs formulated with Lipid M were able deliver EGFP and ciliary neurotrophic factor (CNTF) mRNA to retinal pigment epithelium (RPE) cells after intravitreal injection. Acute inflammation was not observed up to 6 hours post injection.