PI(3,4,5)P3 18:0/20:4

Artikelnummer: ECH-P-3924
Artikelname: PI(3,4,5)P3 18:0/20:4
Artikelnummer: ECH-P-3924
Hersteller Artikelnummer: P-3924
Alternativnummer: ECH-P-3924-100UG,ECH-P-3924-1MG,ECH-P-3924-500UG
Hersteller: Echelon Biosciences
Kategorie: Molekularbiologie
PI(3,4,5)P3 (Phosphatidylinositol 3,4,5-trisphosphate) 18:0/20:4 is a synthetic, purified PI(3,4,5)P3 with stearoyl and arachidonoyl acyl groups. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2.
Product Keywords: 1-Stearoyl-2-arachidonoyl-phosphatidylinositol 3,4,5-trisphosphate, PtdIns(3,4,5)P3 (18:0/20:4), PI(3,4,5)P3 (18:0/20:4), or PIP3 Bulk discounts available, please email echelon echelon-inc.com for information.

Documents

Technical Data Sheet
Anwendungsbeschreibung: Categories: Lipids. Related: PI(3\,4\,5)P3. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination