GroPI(4)P

Artikelnummer: ECH-P-4000
Artikelname: GroPI(4)P
Artikelnummer: ECH-P-4000
Hersteller Artikelnummer: P-4000
Alternativnummer: ECH-P-4000-100UG,ECH-P-4000-1MG,ECH-P-4000-500UG
Hersteller: Echelon Biosciences
Kategorie: Molekularbiologie
Glycerophosphoinositol 4-phosphate (GroPI(4)P) is a synthetic, purified PI(4)P without acyl chains at the 1- and 2-positions of the glycerol. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4,5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.

Storage

-20C

Featured in Publications

1) Zizza, P., C. Iurisci, et al. (2012). Phospholipase A2 IValpha regulates phagocytosis independent of its enzymatic activity. J Biol Chem 287(20): 16849-16859. 2) Vessichelli, M., et al. (2017). The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses. Journal of Biological Chemistry 292(31): 12828-12841. 3) Varone, A., et al. (2019). A signalling cascade involving receptor-activated phospholipase A2, glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility. Cell Communication and Signaling 17(1): 20. Product Keywords: Glycerophosphatidylinositol 4-phosphate, GroPtdIns(4)P, GroPI(4)P, or GroPI4P Bulk discounts available, please email echelon echelon-inc.com for information.

Documents

Technical Data Sheet
Anwendungsbeschreibung: Categories: Lipids. Related: Glycerolphosphoinositide. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination