PI(4,5)P2 diC16

Artikelnummer: ECH-P-4516
Artikelname: PI(4,5)P2 diC16
Artikelnummer: ECH-P-4516
Hersteller Artikelnummer: P-4516
Alternativnummer: ECH-P-4516-100UG,ECH-P-4516-1MG,ECH-P-4516-500UG
Hersteller: Echelon Biosciences
Kategorie: Molekularbiologie
Phosphatidylinositol 4,5-bisphosphate diC16 (PI(4,5)P2 diC16) is a synthetic, purified dipalmitoyl PI(4,5)P2. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K).

Featured in Publications

1) Hodgkin, M. N., M. R. Masson, et al. (2000). Phospholipase D regulation and localisation is dependent upon a phosphatidylinositol 4,5-biphosphate-specific PH domain. Curr Biol 10(1): 43-6. 2) Ozaki, S., D. B. DeWald, et al. (2000). Intracellular delivery of phosphoinositides and inositol phosphates using polyamine carriers. Proc Natl Acad Sci U S A 97(21): 11286-11291. 3) Gwanyanya, A., K. R. Sipido, et al. (2006). ATP and PIP2 dependence of the magnesium-inhibited, TRPM7-like cation channel in cardiac myocytes. Am J Physiol Cell Physiol 291(4): C627-35. 4) Liu, Z., T. Klaavuniemi, et al. (2011). Distinct roles of four gelsolin-like domains of Caenorhabditis elegans gelsolin-like protein-1 in actin filament severing, barbed end capping, and phosphoinositide binding. Biochemistry 49(20): 4349-60. Alternate Names: Dipalmitoyl Phosphatidylinositol 4,5-bisphosphate, PtdIns(4,5)P2 (16:0/16:0), PI(4,5)P2 C16, or PIP2 Bulk discounts available, please email echelon echelon-inc.com for information.

Documents

Technical Data Sheet
Anwendungsbeschreibung: Categories: Lipids. Related: diC16, PI(4\,5)P2. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination