PI(5)P diC4
Artikelnummer:
ECH-P-5004
Produktübersicht
Artikelname:
PI(5)P diC4
Artikelnummer:
ECH-P-5004
Hersteller Artikelnummer:
P-5004
Alternativnummer:
ECH-P-5004-100UG,ECH-P-5004-1MG,ECH-P-5004-500UG
Hersteller:
Echelon Biosciences
Kategorie:
Molekularbiologie
Produktbeschreibung
Phosphatidylinositol 5-phosphate diC4 (PI(5)P diC4) is a synthetic, purified dibutanoyl PI(5)P. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. Storage -20 C Featyred in Publications 1) Guo, J., M. R. Wenk, et al. (2003). Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles. Proc Natl Acad Sci U S A 100(7): 3995-4000. 2) Pendaries, C., H. Tronchere, et al. (2006). PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection. Embo J 25(5): 1024-34. 3) Ramel, D., F. Lagarrigue, et al. (2011). Shigella flexneri Infection Generates the Lipid PI5P to Alter Endocytosis and Prevent Termination of EGFR Signaling. Sci. Signal. 4(191): ra61-. 4) Boal, F. d. r., A. Puhar, et al. (2016). PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment. Cell Reports., doi:10.1016/j.celrep.2015.12.079 Alternate Names: D-myo-Phosphatidylinositol 5-phosphate, Dibutanoyl Phosphatidylinositol 5-phosphate, PtdIns(5)P C4, PI(5)P C4, or PI5P Bulk discounts available, please email echelon echelon-inc.com for information. Documents Technical Data Sheet
Anwendungsbeschreibung
Anwendungsbeschreibung:
Categories: Lipids. Related: diC4, PI(5)P. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination
